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TB-500

Thymosin β4 synthetic fragment

Overview

Overview

TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4. It is widely studied for its role in actin sequestration and its influence on cell migration and differentiation in vitro.

Background

History

TB-500 has been characterized in the peer-reviewed literature over multiple decades of investigation. This section aggregates published citations spanning its identification, structural characterization, and subsequent laboratory research programs. See the References section below for the full bibliography.

Chemistry

Mechanism of action

Sequence
SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Molecular Formula
C212H350N56O78S
Molecular Weight
4963.44 g/mol
CAS Number
77591-33-4
Appearance
White lyophilized powder
Purity
99.4% by HPLC

TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4. It is widely studied for its role in actin sequestration and its influence on cell migration and differentiation in vitro.

Literature

Published research

Preclinical

Animal studies

No preclinical / animal-model citations catalogued for TB-500.

Clinical

Human studies

No human-subject citations catalogued for TB-500.

Synthesis

Current scientific understanding

The current body of literature on TB-500 continues to evolve. BioNex aggregates published sources for laboratory research reference only; nothing on this page is a medical claim, dosage guidance, or therapeutic recommendation.

References

References

  1. Thymosin beta-4 activates integrin-linked kinase — Bock-Marquette I. et al., Nature, 2004 · source
FAQ

Frequently asked questions

Scientific disclaimer

This page aggregates published scientific literature and analytical information for laboratory research reference only. Content is not evaluated by the FDA and does not constitute medical advice, dosage guidance, treatment claims, or administration instructions. Compounds are supplied strictly for in-vitro laboratory research by qualified professionals.