Manufacturing
How BioNex compounds are made.
A six-stage synthesis-to-release process engineered for reproducibility, purity, and traceability.
- 01Solid-phase synthesis
Fmoc-based SPPS on automated synthesizers with argon-purged reaction vessels.
- 02Cleavage & precipitation
TFA-based cleavage cocktails matched to sequence chemistry; cold-ether precipitation.
- 03Preparative HPLC
Reverse-phase preparative HPLC with UV-triggered fractionation to ≥ 99% target purity.
- 04Lyophilization
Controlled-shelf lyophilization to sub-1% residual moisture for stable storage.
- 05Analytical QC
Independent HPLC, LC-MS, and appearance testing per SKU with archived spectra.
- 06Batch release
COA issued against a serialized batch number and published to /batch.